tlooto
Sign up
Open AccessMedicineBiology

Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer’s Disease

L. Lue, Y. Kuo, A. Roher, L. Brachova, Yong Shen, L. Sue, T. Beach, J. Kurth, R. Rydel, J. Rogers

1999.9.1AMERICAN JOURNAL OF PATHOLOGY

DOI: 10.1016/s0002-9440(10)65184-x

tlooto Summary

Investigation revealed that Aβ40, whether in soluble or insoluble form, was a particularly useful measure for classifying ND, HPC, and AD patients compared with Aβ42, and it was found that concentrations of soluble Aβ clearly distinguished HPC from AD patients and were a strong inverse correlate of synapse loss.

Abstract

Abstract is not available.

Citation format

LUE, L., et al. Soluble amyloid β peptide concentration as a predictor of synaptic change in alzheimer’s disease. AMERICAN JOURNAL OF PATHOLOGY, 1999, 155: 853–862.