Longfa Kou, Jin Sun, Yinglei Zhai, Zhonggui He
tlooto Summary
The endocytic pathways are introduced, new technologies to confirm the specific endocytical pathways are presented and factors for pathway selection are discussed, which may provide new thoughts for the design of novel multifunctional nanomedicines.
Abstract
Nanomedicines employ multiple endocytic pathways to enter cells. Their following fate is interesting, but it is not sufficient understood currently. This review introduces the endocytic pathways, presents new technologies to confirm the specific endocytic pathways and discusses factors for pathway selection. In addition, some intriguing implication about nanomedicine design based on endocytosis will also be discussed at the end. This review may provide new thoughts for the design of novel multifunctional nanomedicines.
Citation format
KOU, Longfa, et al. The endocytosis and intracellular fate of nanomedicines: Implication for rational design. Asian Journal of Pharmaceutical Sciences, 2013, 8: 1–10.