MedicineBiology

Buneeva Oa, Medvedev Ae

2011.5.1Biomeditsinskaya Khimiya

DOI: 10.18097/pbmc20115703246

tlooto Summary

Special attention is paid to the inactivation of mitochondrial enzymes, mutations in mitochondrial and nuclear DNA, and genomic and proteomic research of mitochondrial proteins in Parkinson's disease and experimental parkinsonism of animals.

Abstract

Mitochondrial structural and functional abnormalities in Parkinson's disease and experimental animal models of this pathology are described. Special attention is paid to the inactivation of mitochondrial enzymes, mutations in mitochondrial and nuclear DNA, and genomic and proteomic research of mitochondrial proteins in Parkinson's disease and experimental parkinsonism of animals.

Citation format

OA, Buneeva; AE, Medvedev. [Mitochondrial disfunction in parkinson's disease]. Biomeditsinskaya Khimiya, 2011, 57: 246–281.