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MedicineChemistry

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

C. Lipinski, F. Lombardo, B. Dominy, P. Feeney

1997.1.15ADVANCED DRUG DELIVERY REVIEWS

DOI: 10.1016/s0169-409x(00)00129-0

tlooto Summary

Experimental and computational approaches to estimate solubility and permeability in discovery and development settings are described and useful predictions are possible in closely related analog series when coupled with experimental thermodynamicsolubility measurements.

Abstract

Abstract is not available.

Citation format

LIPINSKI, C., et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. ADVANCED DRUG DELIVERY REVIEWS, 1997, 46: 3–26.