Gradient selection in inverse heteronuclear correlation spectroscopy

After a brief theoretical description, new gradient‐selected, proton‐detected heteronuclear correlation sequences are introduced. The gs‐HMBC and gs‐Relayed‐HMQC are closely related to the original gs‐HMQC proposed by Hurd and John. A new approach to obtain pure absorption line shapes in gradient selected spectroscopy is used to measure phase‐sensitive gs‐HMQC spectra, to carry out multiplicity editing in HSQC spectra and to distinguish direct and long‐range correlations in HMQC/HSQC–TOCSY spectra.