Transcatheter arterial chemoembolization combined with CT-guided percutaneous intratumor ethanol injection for liver metastases

Objective To study the clinical efficiency of transcatheter arterial chemoembolization (TACE) combined with CT-guided percutaneous intratumor ethanol injection(PEI) for liver metastases. Methods Forty-eight patients (132 lesions) with inoperable liver metastases were randomly divided into two groups. Twenty-five patients(68 lesions, study group) were treated with TACE and CT-guided PEI. Twenty-three patients (64 lesions, control group) were treated with single TACE. All the cases were followed up from 10 to 43 months, and the efficiency of the two groups was compared with. Results Tumor shrinking rate of study group and control group was 66.2% and 48.4%, respectively. Survival rate of 1 year, 2 years and 3 years of the two groups was 92.0%,80.0%, 64.0% and 78.3%, 65.2%, 47.8%, respectively. Local recrudescent rate of the two groups was 16.0% and 39.1%, respectively. There was significant difference between the two groups in all above-mentioned. Conclusion TACE combined with CT-guided PEI could cooperate with each other in the treatment of liver metastases, and the efficiency of it was better than single TACE.