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MedicineChemistry

Chapter 33. Plasma Protein Binding of Drugs

R. Olson, D. Christ

1996Annual Reports in Medicinal Chemistry

DOI: 10.1016/s0065-7743(08)60472-8

tlooto Summary

This chapter discusses the structures of drug-binding proteins, particularly human serum albumin (HSA) and alpha-1-acid glycoprotein (AAG), the relationship between ligand structure and protein binding and the effect of plasma protein binding on drug disposition and pharmacological activity.

Abstract

Abstract is not available.

Citation format

OLSON, R.; CHRIST, D. Chapter 33. plasma protein binding of drugs. Annual Reports in Medicinal Chemistry, 1996, 31: 327–336.