S. D’Oronzo, R. Coleman, Janet E Brown, F. Silvestris
2018.11.6Journal of Bone Oncology
tlooto Summary
Bone metastases negatively impact on patients’ quality of life (QoL) and survival and bone turnover modulators reduce the risk of skeletal complications and improve pain.
Abstract
Highlights • Bone metastases negatively impact on patients’ quality of life (QoL).• Skeletal related events have a detrimental effect on both QoL and survival.• Both local and systemic treatments are often required to manage bone metastases.• Bone turnover modulators reduce the risk of skeletal complications and improve pain.• Novel agents may deserve further investigation for the management of bone metastases.
Citation format
D’ORONZO, S., et al. Metastatic bone disease: Pathogenesis and therapeutic options. Journal of Bone Oncology, 2018, 15: 004–004.