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The use of animal models in expression pharmacogenomic analyses.

Rothberg Be

2001PHARMACOGENOMICS JOURNAL

DOI: 10.1038/sj.tpj.6500008

tlooto Summary

This review will address expression pharmacogenomics in the context of those animal model systems commonly used for pharmacokinetic, pharmacodynamic and toxicologic analyses in order to streamline drug development by triaging towards lead compounds and clinical candidates that maximize efficacy while minimizing safety risks.

Abstract

Abstract is not available.

Citation format

BE, Rothberg. The use of animal models in expression pharmacogenomic analyses. PHARMACOGENOMICS JOURNAL, 2001, 1: 48–58.