Influence of glucose concentration on blood optical properties in THz frequency range

Non-invasive blood glucose sensing is still actual scientific task for more safe and comfort diabetes care. This article shows correlation between blood optical properties and its glucose concentration. The transmission spectra of whole blood have been studied by the time-domain THz spectroscopy in the frequency range from 0.3 to 0.5 THz. Biosamples were produced from the same person with the diabetes mellitus during a short time period after the insulin injection have been used. Frequency dispersions of blood optical properties are obtained. Based on frequency dispersions, the dependences of blood glucose concentrations with the refractive index and permittivity are presented. This work is a part of the complex investigation, which focuses on the development of a non-invasive glucose measuring technique. Registering dependences between blood glucose level and blood optical parameters allows for using the reflective spectroscopy techniques in future for non-invasive blood glucose level sensing.