Dong Guo, Ying Meng, Xiaoming Jiang, Zhimin Lu
2023.1.1Cell Insight
tlooto Summary
Hexokinases play pivotal roles in glucose metabolism through canonical functions of hexokinases as well as in immune response, cell stemness, autophagy, and other cellular activities through non canonical functions.
Abstract
Glucose metabolism is indispensable for cell growth and survival. Hexokinases play pivotal roles in glucose metabolism through canonical functions of hexokinases as well as in immune response, cell stemness, autophagy, and other cellular activities through noncanonical functions. The aberrant regulation of hexokinases contributes to the development and progression of pathologies, including cancer and immune diseases.
Citation format
GUO, Dong, et al. Hexokinases in cancer and other pathologies. Cell Insight, 2023, 2.