Metabolic Syndrome In Covid-19 Critically Ill Patient And Its Association With Prognosis

present study evaluated vitamin D status and its association with clinical outcomes in the intensive care unit (ICU). Methods: This prospective, multicenter study was conducted at seven ICUs. Serum vitamin D of the patients was measured within 24 hours after ICU admission, and they were followed-up in terms of disease severity based on the scores of acute physiologic assessment and chronic health evaluation II (APACHE II), sequential organ failure assessment (SOFA), and nutritional status (NUTRIC). Results: 236 patients were enrolled in the study, and 69.1% had lower vitamin D levels than 20 ng/ml upon ICU admission.The patients with VDD had higher disease severity (mean APACHE II score: 15.41 ± 6.49; P ¼ 0.026). In addition, the mortality rate was higher in the patients with VDD (P ¼ 0.002), and VDD was independently associated with mortality (OR: 4.83; 95% CI: 1.63-14.27; P ¼ 0.004). Conclusion: According to the results, VDD was highly prevalent in critically ill patients and associated with increased disease severity. Further- more, VDD was an independent risk factor for mortality.