Hiroaki Sasaki, T. Nagai, Takayuki Nakamura, Yusuke Umezawa, Kazuhiko Miki, Haruki Yamada, K. Koyama, Kunio Takahashi, K. Kinoshita
2023HETEROCYCLES
tlooto Summary
Ginkgetin and sciadopitysin have been shown to exhibit influenza virus sialidase inhibitory activity, and glycoconjugates consisting of biflavonoids and sugars are synthesised and inhibited.
Abstract
– Ginkgetin ( 1 ) and sciadopitysin ( 2 ) have been shown to exhibit influenza virus sialidase inhibitory activity. We report the synthesis and sialidase inhibitory activity of glycoconjugates consisting of biflavonoids ( 1 , 2 ) and sugars: 2-keto-3-deoxy-D -glycero- D -galactonononic acid (KDN, 3 ), N -acetyl- D - glucosamine (GlcNAc, 4 ), and N -acetyl- D -lactosamine (LacNAc, 5 ). The glycoconjugates ( 18R
Citation format
SASAKI, Hiroaki, et al. Sialidase inhibitory activity of synthesized biflavonoid glycoconjugates. HETEROCYCLES, 2023.