Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer (2 | AcademicGPT, tlooto

A small molecule compound is identified, N6F11, that selectively triggered degradation of glutathione peroxidase 4 (GPX4), a ferroptosis repressor, in tumor cells and not immune cells, which may estab (2023), Science Translational Medicine, Li Jingbo | AcademicGPT, tlooto for Academic and Research