MedicineEnvironmental Science
J. E. Lima, N. C. Moreira, E. Sakamoto-Hojo
2022MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
tlooto Summary
This review focuses on the mechanisms by which oxidative stress, mitochondrial dysfunction, ER stress, and inflammation are involved in the pathophysiology of T2D, highlighting the importance of the antioxidant response and DNA repair mechanisms counteracting the development of the disease.
Abstract
Abstract is not available.
Citation format
LIMA, J. E.; MOREIRA, N. C.; SAKAMOTO-HOJO, E. Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 2022, 874-875: 503437.