F. Coperchini, L. Chiovato, L. Croce, F. Magri, M. Rotondi
2020.5.11CYTOKINE & GROWTH FACTOR REVIEWS
tlooto Summary
The chemokine system is involved in the pathogenesis of severe clinical sequelae of COVID-19, similarly to SARS and MERS, similarly to SARS and MERS.
Abstract
Highlights • COVID-19 pandemic is raging worldwide and is putting health-care systems under severe strain.• The “cytokine storm” and the subsequent ARDS result from the effects of the combination of several immune-active molecules.• The “cytokine storm” is the most dangerous and potentially life-threatening event related to COVID-19.• The chemokine system is involved in the pathogenesis of severe clinical sequelae of COVID-19, similarly to SARS and MERS.
Citation format
COPERCHINI, F., et al. The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system. CYTOKINE & GROWTH FACTOR REVIEWS, 2020, 53: 25–32.