Cytokine storm warning and treatment progress on COVID-19

At present, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading around the world, and the number of deaths is rapidly rising More and more studies show that the progression of critically ill patients is closely related to the occurrence of cytokine storm This review summarizes the concepts and mechanisms of coronavirus disease-2019 (COVID-19)-related cytokine storm, early warning, clinical manifestations, laboratory test indicators, as well as drugs and therapies with clinical application evidence or potential application prospects, in order to reduce COVID-19 patients to turning into critically ill ones and the mortality rate, and to provide evidence for early diagnosis and treatment of cytokine storm © 2020, Chinese Journal of New Drugs Co Ltd All right reserved