Colorectal Cancer Epidemiology: Recent trends and Impact on Outcomes.

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related death in the world with an estimated number of 1.8 million new cases and about 881,000 deaths worldwide in 2018. The epide-miology of CRC varies significantly between different regions in the world as well as between different age, gender and racial groups. Multiple factors are involved in this variation including risk factor exposure, demographic variations in addi-tion to genetic susceptibility and genetic mutations and their effect on the prognosis and treatment response. In this mini review, we are discussing the recent epidemiological trend including the incidence and mortality of colorectal cancer world-wide and the factors affecting these trends.