Medicine

Reversible male infertility with valproate use: A review of the literature

E. Tallon, L. O'Donovan, N. Delanty

2021.3.31Epilepsy & Behavior Reports

DOI: 10.1016/j.ebr.2021.100446

tlooto Summary

Valproate therapy can result in reduced sperm count, motility and abnormal morphology, which may be dependent on the dose and the duration of Valproate treatment.

Abstract

Highlights • Valproate therapy can result in reduced sperm count, motility and abnormal morphology.• Valproate’s adverse effects on male fertility are reversible in some patients.• Abnormalities may be dependent on the dose and the duration of Valproate treatment.

Citation format

TALLON, E.; O'DONOVAN, L.; DELANTY, N. Reversible male infertility with valproate use: A review of the literature. Epilepsy & Behavior Reports, 2021, 16.