Qingrui Huang, Jiawei Zeng, Jinghua Yan
2021.2.1Journal of Genetics and Genomics
tlooto Summary
Keynotes in mRNA vaccine development are outlined, recently published data on COVID-19 mRNA vaccine candidates are discussed, focusing on those in clinical trials and future potential challenges are analyzed.
Abstract
The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two mRNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive results. In this review, we outline keynotes in mRNA vaccine development, discuss recently published data on COVID-19 mRNA vaccine candidates, focusing on those in clinical trials and analyze future potential challenges.
Citation format
HUANG, Qingrui; ZENG, Jiawei; YAN, Jinghua. COVID-19 mrna vaccines. Journal of Genetics and Genomics, 2021, 48: 107–114.