Nanoemulsion as Oral Drug Delivery - A Review.

OBJECTIVE The stability and delivery of the drugs remains one of the key hurdles in the present situation. The present study depends on the design of a novel nanoemulsion drug-delivery system that would encapsulate a drug and to improve drug stability. The charisma of nanotechnology is majorly due to the smallest particle size at the nanoscale.

METHODS The nanoemulsions attention is focused to emphasize formulation aspect, method of preparation characterization techniques, evaluation parameters and various application of the nanoemulsions, several techniques are to be used for preparation of nanoemulsions like microfluidization, high pressure homogenization, low energy emulsification and solvent evaporation method and their parameters to be characterized.

RESULTS The design of effective formulations for drugs is being applied to enhance the solubility and bioavailability of water insoluble drugs. The nanosized droplets leading to an enormous considerable attraction for this formulation, for the delivery of hydrophilic as well as hydrophobic drug as drug carriers because of its improved drug solubilization capacity, long shelf life, ease of preparation and improvement of bioavailability of drugs.

CONCLUSION The application of these nanoformulation preparations, limitations, their advantages and disadvantages as nanoemulsion will solve the various problems that current therapeutic agents fronting and has been open new scenario to formulate nanoemulsions with various therapeutic agents with heightened competence along with oral drug delivery to treat diseases in near future.