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Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer.

Y. Imamura, T. Mukohara, Y. Shimono, Y. Funakoshi, N. Chayahara, M. Toyoda, N. Kiyota, S. Takao, S. Kono, T. Nakatsura, H. Minami

2015.4.1ONCOLOGY REPORTS

DOI: 10.3892/or.2015.3767

tlooto Summary

3D- Cultured cells forming dense MCSs may be better than 2D-cultured cells in simulating important tumor characteristics in vivo, namely hypoxia, dormancy, anti-apoptotic features and their resulting drug resistance.

Abstract

Abstract is not available.

Citation format

IMAMURA, Y., et al. Comparison of 2d- and 3d-culture models as drug-testing platforms in breast cancer. ONCOLOGY REPORTS, 2015, 33 4: 1837–43.