BiologyChemistryMedicine

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells.

Andrew S. Dixon, Marie K. Schwinn, M. Hall, Kris Zimmerman, Paul E. Otto, T. Lubben, Braeden L. Butler, B. Binkowski, T. Machleidt, Thomas A. Kirkland, Monika G Wood, C. Eggers, L. Encell, K. Wood

2016.2.19ACS Chemical Biology

DOI: 10.1021/acschembio.5b00753

tlooto Summary

NanoBiT provided a means to measure pharmacology of kinase inhibitors known to induce the interaction between BRAF and CRAF and that the reporter responds reliably and dynamically in cells.

Abstract

Abstract is not available.

Citation format

DIXON, Andrew S., et al. Nanoluc complementation reporter optimized for accurate measurement of protein interactions in cells. ACS Chemical Biology, 2016, 11 2: 400–8.