Assist in finding sources on LPS-induced chronic systemic inflammation in Sprague-Dawley rats. - tlooto, The Most Powerful AcademicGPT

You have requested to find and obtain the article titled Induction of Chronic Subclinical Systemic Inflammation in Sprague-Dawley Rats Stimulated by Intermittent Bolus Injection of Lipopolysaccharide. Based on the information and context provided, I am unable to directly deliver the full text of this article. However, I can guide you efficiently in your search and provide relevant background about the topic as reflected by published research in Sprague-Dawley rats using lipopolysaccharide (LPS) to induce subclinical or systemic inflammation. Sprague-Dawley rats are one of the most widely used outbred laboratory rat strains for biomedical research, including studies of inflammation, due to their well-characterized genetics and physiology[1]. LPS, a component of the outer membrane of Gram-negative bacteria, is commonly utilized to experimentally induce systemic inflammation and immune activation in rodents. Previous studies have established that repeated or intermittent administration of