Catalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsSynthesis of Indole Derivatives
Ana K García-Dueñas, Edson Daniel Herández-Velázquez, Jaime G Ibarra-Gutiérrez, Rafael Ortíz‐Alvarado, Jesús Adrián López, L. Chacón-García, Gabriel Merino, Fernando Murillo, C. Solorio-Alvarado
2026.11.12Organic Chemistry Frontiers
Abstract
We report a regiodivergent gold(I)-catalysed cycloisomerisation of terminal 2-alkynyl anilines that affords either C2-o-tolylindoles via a [3,4]-sigmatropic rearrangement or C2/C3-benzylindoles via [1,2]-benzylic migration, where the selectivity is totally controlled by...
Citation format
GARCÍA-DUEÑAS, Ana K, et al. Regiodivergent gold(i)-catalysed rearrangements in indole synthesis. Organic Chemistry Frontiers, 2026, 13(2): 343–349.